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Acetifizz

Effervescent Tablets (600mg N-Acetylcysteine)

Overview:
Acetifizz is an effervescent tablet that serves as a powerful mucolytic, expectorant, and antioxidant, designed specifically to manage respiratory conditions by promoting clearer airway pathways. The active ingredient, N-Acetylcysteine (600 mg), is recognized for its ability to break down mucus, enhancing the clearance of secretions and supporting respiratory health. Acetifizz is particularly effective for individuals suffering from chronic respiratory issues that lead to mucus hypersecretion.

Key Benefits:

  1. Mucolytic Action:
    • Breaking Disulfide Bonds: Acetifizz works by breaking the disulphide bonds present in mucus, reducing its viscosity and allowing easier expectoration. This is particularly beneficial in conditions involving chronic mucus production such as pneumonia, chronic bronchitis, cystic fibrosis, and emphysema.
    • Facilitates Airway Clearance: The reduction in mucus viscosity facilitates easier mucus clearance from the lungs and airways, improving breathing efficiency.
  2. Anti-Inflammatory Properties:
    • Reduction in Inflammation: Acetifizz reduces the production of inflammatory cytokines (such as IL-6), helping to mitigate the inflammatory responses often associated with respiratory conditions. This action not only helps improve respiratory health but also minimizes oxidative stress that can worsen symptoms.
  3. Antioxidant Effects:
    • Boosts Glutathione Levels: N-Acetylcysteine (NAC), the active ingredient, is a precursor to glutathione—one of the body’s most powerful antioxidants. Acetifizz helps increase intracellular cysteine levels, boosting glutathione synthesis and scavenging harmful reactive oxygen species (ROS), which are often elevated in patients with respiratory distress.
    • Supports Renal Health: There is evidence suggesting that Acetifizz can temporarily improve renal function in patients with hepatorenal syndrome (HRS), highlighting its antioxidant potential beyond just respiratory health.

Use Cases:

  • Chronic Respiratory Conditions: Ideal for managing chronic respiratory diseases like chronic bronchitis, tracheobronchitis, and cystic fibrosis, where mucus clearance is crucial for symptom relief.
  • Post-Surgical and Critical Care: Useful in tracheostomy care to maintain airway patency and prevent mucus plugging.
  • Adjunctive Care in Sinusitis: Helps manage sinusitis and rhinosinusitis by improving sinus drainage, enhancing mucociliary function, and reducing congestion.

Dosage:
Dissolve one Acetifizz effervescent tablet in 250 ml of room temperature water, twice daily. This dosage helps ensure optimal mucolytic action and provides consistent relief from symptoms.

Flavour:
Lychee, providing a pleasant taste experience for improved patient compliance.

Safety Profile:
Acetifizz is well-tolerated with a favorable safety profile. It is effective in combination with LAMA/LABA/ICS treatments, reducing the risk of COPD exacerbations and hospitalizations, as highlighted in the GOLD 2023 Report.

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